On the 19th July, IYA team including Prof Kambhampati Subrahmanyam, Sri DR Kaarthikeyan and Ravi Tumuluri visited Rajarajeshwari Temple and paid their respects to Sri Sri Sri Jayendra Puri Mahaswamiji, the present pontiff of Sri Kailash Ashrama Mahasamshtana. Sri Sri Sri Tiruchi Swamigal was the…
129-OR: Diabetes Prevention through Yoga-Based Lifestyle: A Pan-India
Randomized Controlled Trial
RAGHURAM NAGARATHNA, C. VENKATA S. RAM, SASIDHARAN K. RAJESH, AMIT
SINGH, VIJAYA MAJUMDAR, SUCHITRA PATIL and HONGASANDRA R. NAGENDRA
Diabetes 2019 Jun; 68(Supplement 1): -.
Objective: The study tested the potency of yoga-based intervention on risk reduction of
Research Design and Methods:
This study is an offshoot of a large, 2 group cluster randomized, translational research trial on 11,212 individuals, aged >20 years, with high-risk (>60) for diabetes on IDRS (Indian diabetes risk score) and type 2 diabetes. The present study included a subgroup of 3,366 prediabetes individuals [A1C range of 5.70-6.49% (39-47 mmol/ mol)]. Eligible individuals were selected by community-based (rural and urban) screening from 29 states/union Indian territories and were cluster randomized. The wait list control group received lifestyle advice. The experimental group performed a validated yoga-based lifestyle intervention developed by a group of 16 yoga and diabetes experts using the Delphi method. The study outcomes, diabetes incidence/prediabetes remission were obtained by respective A1c values >6.5% (48 mmol/mol) or <5.7% (38 mmol/mol) (normoglycemia) at 3 months of follow-up.
At 3 months of follow-up, 11.2% of the yoga-intervention group and 21.6% of the control group developed diabetes (p<0.05); the relative risk reduction (RRR) was 47% (95% CI: 26-70). Interestingly, the intervention resulted in an effective shift to a normal range of A1c values in 52.0% of individuals as compared to only 39.9% in the control (p<0.05). Yoga-intervention was found to be beneficial for both the normal BMI (<23 Kg/m2) and the overweight/obese sub-groups (≥23 Kg/m2), as indicated by the respective RRRs of 69% (95% CI: 52-85) and 51% (95% CI: 32-70).
This is the first report on the effectiveness of a yoga-based life style intervention for remission of prediabetes and prevention of diabetes. The intervention was adequately effective for normal and overweight/obese subgroups. The short-term findings demand the need for longer follow-up. We speculate positive long-term outcomes based on the reported effects of yoga on self-control and feeding behavior.
Disclosure Raghuram Nagarathna:
None. C. Venkata Ram: None. Sasidharan Rajesh: None. Amit Singh: None. Vijaya Majumdar: None. Suchitra Patil: None. Hongasandra Nagendra: None.
The Ministry of Ayurveda, Yoga and Naturopathy, Unani, Siddha and Homoeopathy; Government of India Ministry of Health and Family Welfare © 2019 by the American Diabetes Association.